Why Do Some People Develop HPPD and Not Others?

Hallucinogen persisting perception disorder (HPPD) is a rare condition that can develop after psychedelic use. HPPD involves persisting visual changes that cause emotional distress and/or impairment to functioning. It is not clear precisely how prevalent the condition is, although its prevalence is considered low. In one study, 4.2% of participants said they experienced continued visual…

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The Role of Memory Recall in Psychedelic Integration

‘Psychedelic integration’ is a somewhat nebulous concept. It is often broadly defined as incorporating what one experienced and learned on psychedelics into everyday life. But this loose definition raises many questions, such as how and why certain aspects of the psychedelic experience are integrated. In other words, what techniques effectively aid such integration, and what…

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Understanding the Risks of 5-MeO-DMT

5-MeO-DMT is widely considered to be the most powerful psychedelic. This is not due to the dosages needed to reach intense altered states – technically, the most potent psychedelic in that respect is LSD, with Salvia divinorum being the most potent naturally occurring psychedelic, given that active doses of Salvinorin A are as low as…

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The State of the World as an Aspect of ‘Set and Setting’

If we want to prioritise ‘set and setting’ (our mindset and physical and social environment) when using psychedelics, then we should be aware of all the possible aspects of our minds and the world that could influence the experience. Realistically, there are innumerable aspects of set and setting, many of which we won’t be aware…

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Nitrous Oxide: A Gas With Mystical, Antidepressant, and Addictive Potential

Nitrous oxide (‘laughing gas’) is a colourless gas with sedative, analgesic, euphoric, dissociative, and (if the dose is right) mystical effects. When used recreationally, the gas comes in canisters, known as ‘nangs’ in Australia and New Zealand, with other street names for the gas including ‘whippets’ (or ‘whippits’) and ‘hippy crack’. There is both a…

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