Kanna: A Natural Antidepressant With Some MDMA-Like Effects

Sceletium tortuosum (or kanna, channa, kougoed) is a psychoactive succulent plant native to South Africa. San hunter-gatherers (or Bushmen), as well as Khoi pastoralists, have used kanna for millennia, before written reports of the uses of these plants by European explorers and settlers emerged. These indigenous peoples have used kanna – the Khoi word for…

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Is DMT an Effective Antidepressant?

Many anecdotal reports suggest that DMT can have antidepressant effects, both in terms of microdosing the substance and by means of larger doses, which result in mystical experiences. While we have seen a flourishing of research into the antidepressant potential of psilocybin (the active ingredient in ‘magic mushrooms’), little research has been carried out into…

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